A recent study published in Frontier Immunology highlights concerns about the long-term impact of COVID-19 mRNA vaccines on cellular immunity. The research focused on individuals receiving a fifth vaccine booster dose and found that while most maintained strong antibody responses, cellular immunity, crucial for preventing severe COVID-19, weakened in many cases. Specifically, after the fifth dose, only half of the participants retained strong cellular immunity. Older individuals, aged 70 and above, were more likely to exhibit a slightly weaker cellular immune response.
The study followed 61 high-risk individuals on hemodialysis from 2021 to 2023, with the first four doses being Pfizer monovalent mRNA vaccines and the fifth dose being the Pfizer-BioNTech bivalent vaccine (Comirnaty Bivalent Original/Omicron BA.4/5). Results indicated a significant decline in cellular immunity after the fifth dose, with potential implications for the overall effectiveness of extended booster vaccination.
The research also revealed that the protective effects from both humoral immunity (antibodies) and cellular immunity established by conventional immunization were profoundly impaired during the extended vaccination course. The study emphasized the potential risks associated with continued use of SARS-CoV-2 boosters.
The blog post further discusses the importance of cellular immunity in the immune system, including the roles of T cells, B cells, and interferon in defending against viruses. It explores how mRNA vaccines, including the spike protein, modified mRNA, lipid nanoparticles, and potential antibody-dependent enhancement, may contribute to the weakening of cellular immunity.
The article concludes by urging a thorough and objective reassessment of the extensive promotion of COVID-19 vaccines and emphasizes the value of non-pharmacological preventive measures and health education about the immune system’s role in combating viruses. It suggests a holistic approach to boost natural immunity based on modern biomedical research and advocates for a comprehensive public health strategy that empowers individuals with essential information.