December 20, 2023

The article delves into the intricate history of smallpox vaccines, challenging the simplistic narrative of their triumph. Part of the “Revisiting the Historical Vaccines” series, the focus is on the multifaceted journey of smallpox vaccination, exploring its evolution and the controversies surrounding it.

The smallpox vaccine, a landmark achievement in medical science, was initially developed by Dr. Edward Jenner in 1796. The article highlights the severity of smallpox, responsible for millions of deaths globally, and introduces the three stages of smallpox vaccines: Jenner’s invention, 18th and 19th-century variations, and modern vaccines.

Dr. Jenner’s story of using cowpox to prevent smallpox, inspired by milkmaids, is scrutinized. The article reveals that the milkmaid narrative was a fabrication by Dr. Jenner’s friend and biographer, John Baron. Additionally, the type of virus in Jenner’s original vaccine is questioned, with evidence suggesting it might have been vaccinia or horsepox rather than cowpox.

The complexity of using different viruses from cows and horses to create vaccines is explored. The lack of standardization, safety testing, and understanding of ingredients in Jenner’s vaccines is discussed, emphasizing the uncertainties surrounding early vaccination practices. Despite these challenges, Jenner’s method of arm-to-arm vaccination gained widespread adoption based on superstition.

The article touches on medical skepticism towards Jenner’s vaccines, with critiques from Dr. Charles Creighton and other prominent medical professionals. Dr. Creighton challenges Jenner’s claims about vaccine efficacy, non-contagiousness, lack of outbreaks, and safety, advocating for more detailed research in pathology to comprehend vaccines fully.

In conclusion, the article sheds light on the untold stories behind the smallpox vaccine, presenting a nuanced perspective grounded in scientific data and historical context. It encourages readers to reevaluate the traditional narrative, fostering a deeper understanding of the complexities within the history of vaccines.